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Thromb Haemost 2014; 112(03): 621-623
DOI: 10.1160/TH13-10-0851
DOI: 10.1160/TH13-10-0851
Letters to the Editor
Risk factors for suboptimal efficacy of 3-factor prothrombin complex concentrates in emergency VKA anticoagulation reversal
Further Information
Publication History
Received:
15 October 2013
Accepted after major revision:
23 April 2014
Publication Date:
20 November 2017 (online)
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References
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- 2 Palareti G, Leali N, Coccheri S. et al. Bleeding complications of oral anticoagulant treatment: an inception-cohort, prospective collaborative study (ISCOAT). Italian Study on Complications of Oral Anticoagulant Therapy. Lancet 1996; 348: 423-428.
- 3 Ageno W, Garcia D, Aguilar MI. et al. Prevention and treatment of bleeding complications in patients receiving vitamin K antagonists, part 2: Treatment. Am J Hematol 2009; 84: 584-588.
- 4 Libby EN, Garcia DA. A survey of oral vitamin K use by anticoagulation clinics. Arch Intern Med 2002; 162: 1893-1896.
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- 8 Baggs JH, Patanwala AE, Williams EM. et al. Dosing of 3-factor prothrombin complex concentrate for international normalized ratio reversal. Ann Pharmacother 2012; 46: 51-56.
- 9 Holland L, Warkentin TE, Refaai M. et al. Suboptimal effect of a three-factor prothrombin complex concentrate (Profilnine-SD) in correcting supra-therapeutic international normalized ratio due to warfarin overdose. Transfusion 2009; 49: 1171-1177.
- 10 Imberti D, Magnacavallo A, Dentali F. et al. Emergency reversal of anticoagulation with vitamin K antagonists with 3-factor prothrombin complex concentrates in patients with major bleeding. J Thromb Thrombolysis 2013; 36: 102-108.
- 11 Imberti D, Barillari G, Biasioli C. et al. Prothrombin complex concentrates for urgent anticoagulation reversal in patients with intracranial haemorrhage. Pathophysiol Haemost Thromb 2008; 36: 259-265.
- 12 Menzin J, Hoesche J, Friedman M. et al. Failure to correct International Normalized Ratio and mortality among patients with warfarin-related major bleeding: an analysis of electronic health records. J Thromb Haemost 2012; 10: 596-605.